Summary
Levels of human erythrocyte catalase activity were determined in 38 patients with
thyroidal dysfunction. In patients with hyperthyroidism, erythrocyte catalase activities
were found to be higher than the levels of normal subjects (P < 0.001). In hypothyroidism,
erythrocyte catalase activities were of the same order as those of normal subjects.
Significantly high positive correlation was found between erythrocytes catalase activity
and the levels of thyroxine (r = 0.5794, n=36, P < 0.001), and slight positive correlation
was detected between catalase activity and the levels of triiodothyronine (r = 0.3978,
n=33, P < 0.05). A decreased erythrocyte catalase activity was observed when erythrocytes
lysate was incubated with thyroid hormones. It was suggested that erythrocyte catalase
activity had close relationship with thyroid state, however, direct effect of thyroid
hormones were not observed on erythrocyte catalase assay system in vitro.
Key-Words
Catalase
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Erythrocyte
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Thyroxine
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Triiodothyronine
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Humans
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Hyperthyroidism
